The use of ADRC biospecimens for research is subject to approval of an ancillary study proposal by the ADRC Biospecimen Committee and availability of the requested specimens. Investigators must have the approval of their local IRB and funding for the shipment and handling of specimens. To submit your request for human tissue specimens, please click the Biospecimen Request button or click here to directly navigate to the Biospecimen Request Form.
ADRC's Biospecimen Review Committee convenes every other month to review requests to use available specimens being housed at UF, which serves as the ADRC biorepository.
We want to keep our process as simple and seamless as possible for you. There are just three easy steps needed to receive biospecimen samples!
Loewenstein, D.A., Curiel, R.E., Wright, C., Sun, X., Alperin, N., Crocco, E., Czaja, S.J., Raffo, A., Penate, A., Melo, J., Capp, K., Gamez, M., Duara, R. (2017). Recovery from Proactive Semantic Interference in Mild Cognitive Impairment and Normal Aging: Relationship to Atrophy in Brain Regions Vulnerable to Alzheimer's Disease. Journal of Alzheimer's disease.PubMed
Ayers, J. I., Fromholt, S., Sinyavskaya, O., Siemienski, Z., Rosario, A. M., Li, A., ... & Ceballos-Diaz, C. (2015). Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice. Molecular Therapy, 23(1), 53-62.Google Scholars
Chakrabarty, P., Li, A., Ceballos-Diaz, C., Eddy, J. A., Funk, C. C., Moore, B., ... & Sacino, A. (2015). IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior. Neuron, 85(3), 519-533.Google Scholars
Park, H. J., Ran, Y., Jung, J. I., Holmes, O., Price, A. R., Smithson, L., ... & Ryabinin, A. E. (2015). The stress response neuropeptide CRF increases amyloid‐β production by regulating γ‐secretase activity. The EMBO journal, 34(12), 1674-1686.Google Scholars
Ran, Y., Ladd, G. Z., Ceballos-Diaz, C., Jung, J. I., Greenbaum, D., Felsenstein, K. M., & Golde, T. E. (2015). Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors. PloS one, 10(6), e0128619.Google Scholars
Rutherford, N. J., Brooks, M., & Giasson, B. I. (2016). Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes. Acta Neuropathologica Communications, 4(1), 80.Google Scholars